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• Anabolic androgenic steroid use has increased over the previous decade, despite its potential for antagonistic effects.
• Other frequent potential antagonistic results embody infertility, hepatotoxicity, psychological abnormalities, and gynecomastia .
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• The affected person underwent successful percutaneous intervention of the right coronary artery.
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Moreover, a part of endothelial dysfunction has been proposed, which may contribute to abnormal vessel reactivity. However, testosterone in physiologic doses may even be helpful in sufferers with angina , have higher ischemic thresholds and improved high quality of life . Short-term intracoronary administration of testosterone induces coronary artery dilation and will increase coronary blood flow in males with established coronary artery illness . Therefore, an interaction of endogenous elements of the patient’s threat profile as properly as the testosterone dosing could additionally be issues of whether or not antagonistic occasions happen.

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We report a case of an acute ST-segment elevation myocardial infarction in a affected person with conventional cardiac risk elements utilizing supraphysiologic doses of supplemental, intramuscular testosterone. In addition, this patient also had polycythemia, doubtless secondary to high-dose testosterone. The affected person underwent profitable percutaneous intervention of the right coronary artery. Physicians and sufferers ought to pay consideration to the scientific penalties of anabolic steroid abuse. Development of an atheromatous plaque perpetuates endothelial dysfunction and promotes platelet aggregation and intracoronary thrombus formation (Ajayi et al 1995; Nieminen et al 1996).

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