Moreover, a part of endothelial dysfunction has been proposed, which may contribute to irregular vessel reactivity. However, testosterone in physiologic doses may even be helpful in sufferers with angina , have larger ischemic thresholds and improved high quality of life . Short-term intracoronary administration of testosterone induces coronary artery dilation and will increase coronary blood move in men with established coronary artery disease . Therefore, an interplay of endogenous elements of the patient’s danger profile in addition to the testosterone dosing may be problems with whether opposed occasions happen.

• The left anterior artery demonstrates a 95% stenosis after the primary septal branch.
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• Ajayi AAL, Mathur R, Halushka PV. Testosterone improve human platelet thromboxane A2 receptor density and aggregation responses.

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We report a case of an acute ST-segment elevation myocardial infarction in a affected person with conventional cardiac danger components utilizing supraphysiologic doses of supplemental, intramuscular testosterone. In addition, this affected person additionally had polycythemia, likely secondary to high-dose testosterone. The patient underwent successful percutaneous intervention of the best coronary artery. Physicians and patients should concentrate on the medical consequences of anabolic steroid abuse. Development of an atheromatous plaque perpetuates endothelial dysfunction and promotes platelet aggregation and intracoronary thrombus formation (Ajayi et al 1995; Nieminen et al 1996).

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